September 20, 2024

Epigenetics Market Size Expected to Reach USD 61.04 Billion by 2033

The global epigenetics market size was valued at around USD 14.65 billion in 2023 and is expected to hit around USD 61.04 billion by 2033, growing at solid CAGR of 15.34% from 2024 to 2033.

The field of epigenetics has emerged as a pivotal area of study, garnering significant attention within the scientific and medical communities. Epigenetics explores the intricate mechanisms that regulate gene expression and cellular function, beyond the underlying DNA sequence. This dynamic interplay between genetic and environmental factors has profound implications for various aspects of health and disease.

Epigenetics | Summary

  • North America dominated the market in 2023, accounting for 39% of global revenue.
  • The Asia-Pacific region is projected to experience significant growth, with a 16.73% CAGR from 2024 to 2033.
  • Reagents were the leading product segment in 2023, comprising 34% of the market.
  • Services are expected to see substantial growth, with a forecasted CAGR of 17.69% during the same period.
  • DNA methylation was the dominant technology in 2023, contributing 46% of the market share.
  • Histone acetylation technology is anticipated to expand at the fastest rate, with a projected CAGR of 18.19%.
  • Oncology was the primary application area in 2023, capturing 70% of the market.
  • The academic research segment held the largest share of the end-use market, accounting for 38%.
  • Clinical research is expected to grow notably, with a projected CAGR of 16.40% during the forecast period.

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Market Growth

Your surroundings and habits, including your diet and level of physical activity, are just as essential to your health as your genes. Epigenetics is the study of how changes in your surroundings and behavior can have an impact on how your DNA function. While epigenetic changes can alter how your body interprets a DNA code, they are reversible and do not alter your DNA sequence like hereditary changes do.

There may be a direct or tangential connection between epigenetic processes and several tumors, cardiovascular disorders, respiratory illnesses, reproductive problems, cognitive impairment, and challenges with autoimmune disorders. Pesticides, heavy metals, hormones, tobacco smoke, radiation, environmental factors, viruses, or inadequate nourishment are just a few of the factors that are becoming more prevalent, which is supporting market expansion.

Regional Analysis

In 2023, North America emerged as the dominant force in the market, commanding a substantial share of 39%. The region’s growth is fueled by several factors, including heightened public awareness, robust medical infrastructure, and significant investments in research and development (R&D). Moreover, the prevalence of chronic illnesses and considerable investments by market players in epigenetic research further amplify regional expansion, creating a conducive environment for continued growth. Additionally, the presence of key industry players like Thermo Fisher Scientific, Inc., Element Biosciences, Inc., Dovetail Genomics LLC., Illumina, Inc., and Promega Corporation in the U.S. market is expected to bolster regional expansion efforts.

Conversely, the Asia Pacific region is poised to experience the most rapid compound annual growth rate (CAGR) of 16.73% from 2024 to 2033. This growth trajectory is driven by increasing demand for genome editing technologies and the prevalence of genetic disorders and diseases across countries such as India and Australia. Furthermore, domestic companies offering epigenetics products and services are attracting investments and funding, further fueling regional growth. For instance, in August 2023, Epigenic Therapeutics, a China-based firm, secured USD 32 million in a Series A financing round. This company specializes in developing next-generation gene modulation therapy utilizing epigenome regulation to address prevalent disorders. The influx of investments among such industry players is anticipated to propel regional expansion efforts in the coming years.

Covid-19’s Impact on the Epigenetics Market

Due to the significance of epigenetics in COVID-19 research, Covid has had a major effect on the growth of the epigenetics industry. For instance, epigenetic changes may be crucial in the onset of coronavirus illness complications, according to research that was published in Clinical Epigenetics in October 2020 under the title “The epigenetic implication in coronavirus infection and therapy.” Even though there are many potential treatments, more study is desperately required to find a workable vaccine or more secure chemotherapy drugs, such as epigenetic therapies, to stop this viral epidemic and develop pre- and post-exposure COVID-19 prophylaxis.

Epigenetics Market Dynamics

Market Drivers: Rising desire for the personalized medicines

The rising incidence of chronic illnesses like cancer, diabetes, and heart disease is one of the key factors fueling development in the epigenetics market. There is increasing interest in creating epigenetic treatments that can target these changes because epigenetic modifications have been related to the onset and spread of these illnesses. The rising desire for personalized medication is another element fueling market expansion. Epigenetic profiling can offer useful data about a person’s propensity for contracting specific illnesses, and this data can be used to create individualized therapy regimens.

Market Restraints: Epigenomic data is only occasionally used in toxicity

Epigenomic information has only been partially applied in the field of toxicology, and our grasp of how epigenomic variability varies across various tissue types and groups has also been limited. To guarantee a thorough knowledge of epigenetic mechanisms that results in precise epigenomic variation mapping, novel methods must be developed. Lack of agreement on a typical epigenome for all tissue and cell types is a significant barrier to the implementation of epigenomic research in toxicology.

Market Opportunities: Technological advancement

Technology advancements that make epigenetic study and analysis more available and cheaper are also helping the market for epigenetics. For instance, recent advances in sequencing tools have made it possible for researchers to examine epigenetic changes at the genome-wide level, which was not feasible until recently. Creating epigenetic biomarkers that can be used to identify illnesses early, track the progression of diseases, and forecast therapy results is also becoming more and more popular.

Overall, the epigenetics market offers plenty of room for expansion for companies in the healthcare sector. There is an expanding need for goods and services that can address epigenetic modifications due to the rising prevalence of chronic illnesses, the rising desire for personalized treatment, and technological advancements.

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Epigenetics Market Top Companies

  • Roche Diagnostics
  • Thermo Fisher Scientific, Inc.
  • Eisai Co. Ltd.
  • Novartis AG
  • Element Biosciences, Inc.
  • Dovetail Genomics LLC.
  • Illumina, Inc.
  • Promega Corporation.
  • Abcam plc.

Recent Developments

  • In November 2023, QIAGEN and Element Biosciences, Inc. strategically partnered to offer comprehensive Next-Generation Sequencing (NGS) workflows utilizing the innovative Element AVITI System.
  • In October 2023, Zenith Epigenetics Ltd. entered into an agreement with Cencora to commercialize the ZEN-3694 program, an epigenetic approach aimed at enhancing the efficacy of cancer treatments in conjunction with existing drugs on the market.
  • In September 2023, NanoString Technologies, a prominent provider of life science tools for discovery and translational research, introduced its latest GeoMx Digital Spatial Profiler (DSP) assay.

Epigenetics Market Segmentations:

By Product

  • Reagents
  • Kits
    • ChIP sequencing kit
    • Whole Genomic Amplification kit
    • Bisulfite Conversion kit
    • RNA sequencing kit
    • Others
  • Instruments
  • Enzymes
  • Services

By Technology

  • DNA Methylation
  • Histone Methylation
  • Histone Acetylation
  • Large non-coding RNA
  • MicroRNA modification
  • Chromatin structures

By Application

  • Oncology
    • Solid tumors
    • Liquid tumors
  • Non-oncology oncology
    • Inflammatory diseases
    • Metabolic diseases
    • Infectious diseases
    • Cardiovascular diseases
    • Others

By End-use

  • Academic Research
  • Clinical Research
  • Hospitals & Clinics
  • Pharmaceutical & Biotechnology Companies
  • Other Users

By Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • MEA

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Healthcare Insights

Healthcare Insights is a premier consulting firm specializing in market research and strategic insights. With a deep understanding of diverse industries, including healthcare, healthcare it, pharmaceuticals, life sciences and clinical trails, our team of experts provides actionable intelligence that drives business growth and innovation. Leveraging advanced analytical tools and methodologies, Healthcare Insights delivers comprehensive market analysis, trend forecasting, and competitive intelligence to help clients navigate complex market landscapes. Our commitment to excellence and accuracy ensures that our clients are equipped with the insights they need to make informed decisions and achieve a competitive edge in their respective markets.

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